When it comes to nitrate and amino acid supplementation pre-workout, there is one major goal that everyone is after: Energy.
Energy can mean different things depending on who you’re asking, but to us, it’s simple — how strong do you feel? How long can you last in the gym before getting fatigued? How intense will your body allow every set to be? The answer to each question is directly related to how much energy you physically have.
How much you walk into the gym with depends largely on what you’re providing your body with. How well-rested and recovered your muscles are plays a big role, and so does the system’s available energy sources. And, naturally, this is where citrulline, arginine, and creatine come into play. NOX-P3, ANX-P3 and N’FUZE can all work together — and here’s how.
Arginine and citrulline go hand-in-hand, as the first is synthesized from the second in order to aid function and performance. Arginine is needed for many reasons, some of which include muscle synthesis, growth hormone production and immune function. The process of conversion is necessary for the body to gain arginine’s benefits, but it comes at a big cost — the process expends a great deal of cellular energy (ATP) and oxygen. During intense exercise, citrulline is broken down quickly as oxygen and ATP are depleted, increasing fatigue and sapping strength. (It’s also worth noting that citrulline can be derived from arginine through nitric oxide production.) A University of Pittsburgh examination in 2004, published in The Journal of Nutrition, outlines the process and notes that supplemental arginine replenishes ATP levels — creating a surplus of energy that directly affects strength, power and endurance during a workout.
Another noteworthy point about the arginine-citrulline relationship is that, during the body’s recycling and conversion between the two, a very important by-product is produced — nitric oxide, which is a massive benefit for vasodilation (the expansion of the blood vessels to better deliver oxygen and nutrients). Because of this, arginine is generally noted as a “precursor” to nitric oxide, as an Austrian laboratory review published in 1999. A study published in Biomedicine and Pharmacotherapy later reaffirmed this in 2002 and noted that arginine is key in vasodilation:
“The main importance of Arg is attributed to its role as a precursor for the synthesis of nitric oxide (NO), a free radical molecule that is synthesized in all mammalian cells from L-Arg by NO synthase (NOS).” — Reference.
The big question, of course, is how can all of this come together to help the individual (that’s you!) have a better workout? Knowing that 1) an arginine surplus means less ATP is spent; 2) ATP stores can actually be IMPROVED with creatine and 3) there are multiple pathways for arginine, citrulline and arginine nitrate, we can combine it all to come up with the answer:
Using ANX-P3 90 minutes pre-workout will use the N3O Synthase pathway, and NOX-P3 an hour later will use a different one to combine the effects of both arginine and arginine nitrate. Meanwhile, N’FUZE 30 minutes pre-workout will provide a super-stable form of creatine to boost ATP. The end result will be an incredible workout that will let the body maximize its cellular oxygen and energy stores for better performance.